This session fosters an interactive global dialogue on shared norms and values for maintaining resources at their highest societal value, with a deep-dive into regional ecosystems and bio-based solutions, focusing on critical issues such as food security, health, poverty reduction, environmental protection, and cultural preservation. We will collaboratively explore a strategic prioritisation for the transformation of essential resources, emphasising the paramount importance of the food and feed first principle and the barriers associated with them, and share tools and resources for data-driven mapping of regional ecosystems. Together, let’s shape a unified approach to the Circularity4All principles, connecting insights from the Global North and South.